N-Glycan Targeted Gene Delivery to the Dendritic Cell SIGN Receptor
نویسندگان
چکیده
منابع مشابه
N-glycan targeted gene delivery to the dendritic cell SIGN receptor.
A novel nonviral gene delivery vector composed of a high-mannose N-glycan conjugated to a polyacridine peptide was prepared. The glycopeptide was designed to bind to plasmid DNA by a combination of polyintercalation and ionic binding, and to the DC-SIGN (dendritic cell-specific intracellular adhesion molecule-3 grabbing nonintegrin) receptor expressed on CHO cells by recognition of the high-man...
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ژورنال
عنوان ژورنال: Bioconjugate Chemistry
سال: 2010
ISSN: 1043-1802,1520-4812
DOI: 10.1021/bc1000824